This is my first post as we start our IVF journey. Our doctor suggested Omnitrope hormone shots as I’m 43 and she’s seen great results for those over 40. Has anyone ever used this? It’s not cheap and my insurance doesn’t cover any of this process. Wondering if people have had great results with this.
Appreciate any feedback!
Editor’s Note:- Call our IVF Center at 817-924-1572
Here we have collected some user reviews on using Omnitrope for IVF-
I can personally vouch for the effectiveness of Omnitrope in my IVF cycle. With my doctor’s recommendation, I used it twice, with varying durations, and saw significant differences in my embryo quality. During my first attempt, I used Omnitrope for 8 days, but unfortunately, the quality of my embryos was poor. However, during my second attempt, I used Omnitrope for 12 days, and the results were astonishing. I retrieved five embryos, three of which were Day 5, 3AB quality. This was an outcome that I never thought possible after experiencing so much failure before.
Despite its high cost, I have decided to use Omnitrope again for my next cycle, as I believe it played a crucial role in the success of my last cycle.
I personally underwent two cycles of IVF, and in both cycles, I used Omnitrope. During the first retrieval, I was able to retrieve around 20 eggs, out of which only 18 were mature. Of those, only 12 were fertilized, and ultimately, I had only 4 blasts. Among these, 2 were normal, 1 was mosaic, and 1 was abnormal.
For the second retrieval, my doctor suggested increasing the dosage of Omnitrope to focus on egg quality. I was initially concerned about the low number of eggs retrieved (7), but my worries were unfounded. All 7 eggs were mature, and 6 of them were fertilized. I ended up with 4 blasts, and all 4 were normal.
Although the cost of Omnitrope was around an additional $1,000, it was still cheaper than undergoing another round of retrieval, and I am glad that I used it for both cycles.
In my personal experience, I used Omnitrope during my second round of IVF along with ICSI, although it’s difficult to determine whether Omnitrope was the sole reason for my improved results. The stimulation protocol with Omnitrope was quite different from the first round, with frequent adjustments to medication dosages, and I was uncertain about the number of eggs that would be retrieved. The first round had proceeded smoothly with all follicles growing well, but unfortunately, no viable eggs were retrieved after genetic testing. My husband had no sperm-related issues, and I was 39 years old during both rounds of egg retrieval.
In the first round without Omnitrope, we had 8 baseline, 11 retrieved (all mature), 6 fertilized, 2 blastocysts, and 0 PGT normal. In the second round with Omnitrope and ICSI, we had 6 baseline, 9 retrieved, 1 mature, and 5 maturing later in the lab, 5 total fertilized via ICSI, 3 blastocysts, and 2 PGT normal.
I am currently awaiting a frozen embryo transfer, but based on my experience, I would recommend trying Omnitrope if your doctor believes it may benefit your situation.
Critical analysis on Omnitrope and IVF
20 years ago, growth hormone treatment added about $5000 to the cost of IVF !
Human growth hormone (HGH) has become an increasingly popular adjunct treatment for infertility, particularly for women undergoing in vitro fertilization (IVF). The use of HGH is thought to improve oocyte and embryo quality, resulting in higher success rates of IVF treatments. However, its use in IVF treatment has long been limited due to its high cost.
Over the past 20 years, the cost of HGH for IVF has dramatically gone down. One of the main reasons for this decrease in cost is the introduction of biosimilar HGH products. Biosimilars are similar in structure and function to original biologic drugs but are manufactured by different companies. They undergo a rigorous regulatory process to ensure that they are safe and effective. The development of biosimilar HGH products has increased competition in the market, which has resulted in a decrease in the cost of HGH.
Moreover, the development of recombinant DNA technology has also contributed to the decrease in HGH cost. With this technology, scientists can produce HGH in a lab, making it more affordable and accessible. This technology has revolutionized the pharmaceutical industry by allowing for the production of biologics, including HGH, at a much lower cost than before.
Another factor contributing to the decrease in HGH cost is the emergence of online pharmacies. Online pharmacies offer a more convenient and cost-effective way to purchase medications, including HGH. Patients can compare prices, read reviews, and order their medications from the comfort of their own home.
The decrease in HGH cost has made it more accessible to patients who were previously unable to afford it. This is particularly important for women who are facing infertility and need IVF treatments. The addition of HGH injections like Omnitrope to IVF treatments can increase the success rates of the treatment, resulting in a higher chance of pregnancy and live births.
In conclusion, the cost of HGH for IVF has dramatically gone down over the past 20 years due to the introduction of biosimilar products, recombinant DNA technology, and the emergence of online pharmacies. This decrease in cost has made HGH more accessible to patients and has increased the success rates of IVF treatments. As technology continues to advance, we can expect the cost of HGH to continue to decrease, making it even more accessible to those who need it.
How To Do IVF Injections with HGH injections like Omnitrope
The story of human growth hormone (hGH) is colorful by drug industry standards. I have good news for those of you who are interested in traveling to Las Vegas for IVF. Dr Russel Foulk, Medical Director of SIRM-LV has expressed a willingness to be receptive to, treatment plans that I recommend for SFS patients Moreover, Dr Foulk has graciously agreed to interact with me during such treatments. I highly recommend Dr Foulk to those of you who, following consultation with me, wish to have me remain involved in the implementation of your treatment. This having been said, the final say in any management decision is always up to the treating physician.
And honestly there is not great info out there about egg quality. Some people think stimming for briefer period of time yields better results while others recommend a long slow stim cycle over almost a month. REs opinions vary a ton in regards to egg quality. My RE said there’s lots of things they are working on now in lab settings to bypass poor quality eggs like switching out the nucleus of one egg with a donor egg (or something like that) so it retains all your DNA but has the necessary mitochondria to assist in the important growing and division stages where most embryos don’t make it when there are poor eggs.
Egg Donation-related, fresh and frozen embryo transfer cycles account for 10%-15% of IVF performed in the United States. The vast majority of egg donation procedures performed in the U.S involve women with declining ovarian reserve. While some of these are done for premature ovarian failure, the majority are undertaken in women over 40 years of age. Recurrent IVF failure due to poor quality” eggs or embryos is also a relatively common indication for ED in the U.S. A growing indication for ED is in cases of same-sex relationships (predominantly female) where both partners wish to share in the parenting experience by one serving as egg provider and the other, as the recipient.
Experts Comments & Resources
Generally, the poor responders should be identified by the fertility doctors before starting an IVF cycle. At our fertility clinic we use ovarian reserve testing to evaluate a woman’s expected response to the stimulating medications. As our basic ovarian reserve screening, we do:
- Antral follicle counts by ultrasound
- Anti-mullerian hormone (AMH) blood tests
- Day 3 FSH, LH and estradiol blood tests
These tests will identify the vast majority of poor responders before they get to an IVF attempt. Identifying the problem in advance allows us an opportunity to do something to improve the response (and the outcome) with the first IVF attempt.
The definition of a poor responder is variable. Regardless of the definition one uses, the basic idea is that poor responders do not respond well to the IVF ovarian stimulation protocol by making a good number of mature follicles. Less mature follicles means less eggs retrieved which results in lower numbers of embryos and less chance to have one that is a “marathon runner” (baby).
For example, women under 35 years old give an average of 12 eggs with IVF. However, poor responders would only produce about 1 to 6 eggs. The chances for success with IVF are very much dependent on two variables – the quantity and the quality of the eggs.
Therefore, if we could come up with a treatment that would help the poor responders to give either more eggs or better quality eggs or both, we would be able to positively impact the chance of having a baby.
Our Experience with Omnitrope for IVF Poor Responders
As IVF specialists, we have seen that various types of supplementation protocols have been used to improve outcomes for IVF poor responders. In my practice, I have been using growth hormone supplementation with Omnitrope for this purpose.
Editor’s Note:- Call our IVF Center at 817-924-1572
I have been using growth hormone for poor responders for many years. Despite its high cost in the past, with the drop in the market price for growth hormone due to more competition in the pharmaceutical marketplace, the cost has come down to about $1000 currently. This change has made it more feasible and potentially a cost-effective addition to the IVF stimulation protocol.
Several studies have shown significantly improved IVF success rates in poor responders who supplement their stimulation with growth hormone. The mechanism by which growth hormone would improve IVF success rates is not clear, but it is believed to be involved in production of steroid hormones in the ovary and in development of ovarian follicles. It is also thought to increase the production of insulin-like growth factor 1 (IGF-1) in the ovaries, which is involved in regulating follicle development, estrogen hormone production, and maturation of eggs.
Based on these findings, I have been using growth hormone supplementation for many of my poor responding IVF patients. Although the success rates are still not as high as seen in normal responders to stimulation, they are significantly improved over the baseline success rates expected in poor responders.
However, whether the additional cost of the growth hormone supplementation is worth it is a more difficult question. While some couples will move on to egg donation because of the high success rates with donor eggs instead of continuing to attempt low-yield IVF with their own eggs, many women who use growth hormone supplementation will still have unsuccessful IVF attempts.
The most effective dosage and duration of growth hormone has not been clarified yet. The published studies have used:
- Doses between 4mg – 24mg, given daily or every other day
- Used it for the first several days of stimulation, or for the entire stimulation phase
Poor ovarian response to stimulation is a difficult problem without a perfect solution at this time. Supplementation with growth hormone like Omnitrope is one way we can try to improve the odds for poor responders.
Larger randomized controlled trials are needed to figure out how much improvement in outcome we can expect by using growth hormone as well as which subgroups of patients could benefit the most.