Testosterone therapy is not a fast solution that will instantly terminate or reverse all indications of low testosterone, yet this does not mean that you will have to wait for months to observe positive changes in your life. So, how long will you have to wait to see results?

The speed at which testosterone injections work in the body will depend on every individual’s system response to the hormone. Even though, there is a timeline that can help understand what is happening during treatment and when one may begin to notice a difference.

  1. The effects on libido will be seen after three weeks and reach their maximum at six weeks.
  2. Changes in erections/ejaculations may take up to six months of testosterone replacement therapy.
  3. Improvements in quality of life may be seen within three to four weeks, while maximum benefits will take longer.
  4. The effects on depressive mood become visible after 3-6 weeks with a maximum after 18-30 weeks.
  5. Insulin sensitivity may enhance within a few days, but modifications in glycemic control will become apparent after 3-12 months.
  6. Changes in fat mass, lean body mass, and muscle strength will be observed within 12-16 weeks, stabilize at 6-12 months, but can still slightly continue over the years.
  7. Effects on inflammation should be seen within 3-12 weeks.
  8. Effects on bone will be detectable after six months, while continuing for at least three years.

These results demonstrate that while the effectiveness of testosterone replacement therapy differs from symptom to symptom, one will experience an improvement in a short period of time compared to living with the long-term effects of low testosterone.

Testosterone injections – Individual results may vary

After beginning testosterone injections, most individuals will begin to see and feel results within 4 to 6 weeks. However, some changes may be experienced sooner. This timeline is only a general guide, and individual results may vary.

Factors such as getting proper sleep, eating well, and exercising can all help to improve the effectiveness of testosterone treatment.

Patients may expect to experience tangible results such as increased energy, muscle growth, reduced stiffness and joint pain, and improved libido.

However, the most important result is not one that can be seen, but rather the balance achieved in the body when testosterone levels are normalized after the first injection.

Testosterone Injection: Effects on triglycerides, RBCs, cholesterol, exercise capacity TIMELINE

Beginning testosterone injections can bring about a number of beneficial changes in a person’s life. Within a few days, insulin sensitivity may improve while sexual drive and libido may increase three weeks later.

In addition, anxiety and aggression may be reduced, while perceived quality of life may improve.

After four weeks, lipid profiles may show a decrease in triglycerides and total cholesterol, and a rise in erections and sexual performance for both men and women.

At six weeks, mood and depression symptoms may be improved, and at three months, erythropoiesis (red blood cell formation) may increase and blood pressure may decrease. Exercise capacity may also improve in men with chronic heart failure. Furthermore, LDL cholesterol may decrease and HDL cholesterol may rise between three and twelve months.

At the six-month mark, bone density may increase, while PSA levels may rise in men. After twelve months, prostate-specific antigen and volume may also rise.


After the first year of treatment for low testosterone, individuals may experience a variety of improved physical and mental benefits. These include an increase in red blood cell production, better glycemic control, improved muscle strength, increased bone density, a more positive outlook, enhanced sex drive, a decrease in body fat, deeper and more restful sleep, sharper mental faculties, a plateau in prostate-specific antigen and volume, improved physical appearance, lower blood pressure, cholesterol, and triglyceride levels, and greater exercise capacity. All of these changes can make a profound difference in quality of life for those who have been suffering from the symptoms of low testosterone.

Do You offer Testosterone Pills?

Testosterone pills are not usually recommended due to the fact that when they are ingested, the digestive enzymes in the stomach begin to break down the active ingredients of the medication, meaning it is not as effective. Additionally, the liver can be impacted by the intake of testosterone pills as the balance of the medication can build up and cause potential health issues.


Many people are eager to experience the positive changes that come with testosterone gels therapy, and often ask when they will start to see results.

The timeline for testosterone gel or cream is roughly the same as with injections, however the effects may take slightly longer to become apparent. This is because, unlike injections which allow the entire dosage to be directly absorbed into the bloodstream, the exact amount of testosterone absorbed through the skin when using a gel or cream is uncertain.

Although some people may feel the effects more quickly with the gel or cream, it is impossible to predict how an individual will respond.

Initially, most people experience an increased sex drive, improved quality of life and reduced anxiety within the first month, although the degree of benefit may differ. Every person’s body processes testosterone differently, so results can vary.

Get Started with Testosterone Replacement Therapy

Low testosterone can be diagnosed through a simple blood test. Once diagnosed, it can be treated with testosterone replacement therapy.

This therapy comes in several forms, including intramuscular injections, sublingual troches (portable lozenges) taken daily, and testosterone cream applied daily to the shoulders, upper arms, or abdomen. Each of these options has its own side effects, advantages, and disadvantages, and the best choice should be made with a thorough discussion between the patient and their doctor.

For more information on how quickly testosterone therapy works, what can be expected from treatment, and how to get tested for low testosterone, a free consultation can be arranged. During this confidential consultation, patients can receive further advice on the best type of testosterone for their needs.

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